With over 30 million treatments worldwide and counting,1 the Restylane line of hyaluronic acid fillers provides natural-looking results by smoothing away facial wrinkles and folds (Restylane,4 Restylane Lyft,5 Restylane Refyne,2 Restylane Defyne3), providing subtle lip enhancement and smoothing the lines around them (Restylane Silk6), and adding lift and volume to the cheeks (Restylane Lyft5).

To ensure a safe procedure, your doctor will talk to you about your medical history to determine if you are an appropriate candidate for treatment. You should not use products within the Restylane family if:

• You have severe allergies with a history of severe reactions (anaphylaxis)

• You are allergic to lidocaine or to any of the gram-positive bacterial proteins used to make hyaluronic acid
• You are prone to bleeding or have been diagnosed with a bleeding disorder

The rate of reactions to Restylane is very low. However, after the treatment, some common injection-related reactions may occur, such as swelling, redness, pain, itching, discoloration, and tenderness at the injection site. These typically resolve spontaneously within a few days after injection into the skin and within a week after the injection into the lips. Other types of reactions are very rare, but about 1 in 2000 treated patients have experienced localized reactions thought to be of a hypersensitive nature. These have usually consisted of swelling at the injection site, sometimes affecting the surrounding tissues. Redness, tenderness, and rarely acne-like formations have also been reported. These reactions have either started a few days after the injection or after a delay of 2 – 4 weeks and have generally been described as mild to moderate and self-limiting with an average duration of two weeks. This text does not contain all the information known about these products. For more information, please consult with your practitioner.

The length of time the effect of a Restylane treatment lasts is very individual and depends on many factors, such as the structure of your skin, lifestyle, age, the degree of perfection demanded, and the injection technique of the practitioner.

Experience indicates that touch-up and follow-up treatments will add to the duration. Most people choose to have a new treatment within a year after the treatment of wrinkles and folds and within six months after a lip enhancement.

The cause of this is not yet known, but there is no reason to believe that this is an immunological reaction. Normally, the swelling is gone within a week after injection into the lips.

The correction will gradually disappear until your skin looks like it did before the treatment. Follow-up injections will help you maintain your correctio

You should not expose the treated area to intense heat (e.g. in a solarium or by sunbathing) or extreme cold for the first few days after the treatment in order to avoid the risk of inflammation as the area has been disturbed. However, once Restylane has integrated into the body, it will adjust to your normal body temperature.